Lange Pharmacology Flashcards, Fourth Edition by Baron Suzanne & Lee Christoph

Author:Baron, Suzanne & Lee, Christoph [Baron, Suzanne]
Language: eng
Format: azw3
ISBN: 9781259837241
Publisher: McGraw-Hill Education
Published: 2017-11-16T16:00:00+00:00

Clinical Uses

Used in the treatment of hypertension and congestive heart failure; also used to treat and prevent diabetic nephropathy.

Side Effects

Hyperkalemia and renal failure in patients with renal insufficiency; hypotension; teratogen (may cause fetal renal damage if used during pregnancy); rash.

Other

Note that, unlike the ACE inhibitors, the ARBs have no effect on the metabolism of bradykinin. Accordingly, they are not associated with a cough or the development of angioedema (both of these side effects are believed to be related to elevated levels of bradykinin).

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